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2011/05/10

Time-course and regional analyses of the physiopathological changes induced after cerebral injection of an amyloid β fragment in rats.

  Authors: Zussy C, Brureau A, Delair B, Marchal S, Keller E, Ixart G, Naert G, Meunier J, Chevallier N, Maurice T, Givalois L.   Abstract: […]
2011/05/09

Behavioural phenotyping of knockout mice for the sigma-1 (σ₁) chaperone protein revealed gender-related anxiety, depressive-like and memory alterations.

  Authors: Chevallier N, Keller E, Maurice T.   Abstract: The sigma-1 (σ₁) protein regulates calcium homeostasis and acts as an endoplasmic reticulum chaperone. It can […]
2010/09/09

Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma 1 (σ1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative.

  Authors: Villard V, Espallergues J, Keller E, Vamvakides A, Maurice T.   Abstract: Tetrahydro-N, N-dimethyl-2, 2-diphenyl-3-furanmethanamine hydrochloride (ANAVEX2-73) binds to muscarinic acetylcholine and sigma(1) (σ(1)) […]